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    Armour Faculty

    Hyun-soon Chong, Ph.D.

    Associate Professor of Chemistry

    Office: 398 Life Sciences Building
    Office Hours:
    Phone: 312.567.3235
    Fax: 312.567.3494
    Email: chong@iit.edu
    Web:

    Expertise

    Education

    • B.S. Kyung Hee University
    • Ph.D. University of North Texas

    Curriculum Vitae

    Research & Major Accomplishments

    My research group is broadly interested in areas of organic synthesis, medicinal chemistry, biochemistry, bioconjugate chemistry, and cell biology. The current work at my laboratory is centered on interdisciplinary research projects aimed at developing safe, effective, and targeted drugs for cancer and neurodegenerative diseases. My lab has developed several promising cancer therapeutic and diagnostic agents with successful preclinical profiles that are favorably compared to the existing cancer drugs. We are also interested in synthetic and mechanistic studies of aziridines and aziridinium ions as reactive intermediate compounds in organic synthesis.

    Current Projects

    Awards/Honors

    Patents

    Books

    Selected Publications

    Song HA, Dadwal M, Sun X, Lee Y, Mick E, Chong HS. Stable aziridinium salts as versatile intermediates: Isolation, regioselective ring opening, and rearrangement. Angew. Chem. Int. Ed. 2009, 48, 1328–1330.

    Chong HS, Song HA, Ma X, Lim SY, Mhaske S, Sun X. Novel bile acid-based polyaminocarboxylates as targeted antitumor agents. Chem. Comm. 2009, 3011–3013.

    Chong HS, Song HA, Birch N, Le T, Lim SY, Ma X. Efficient synthesis and evaluation of bimodal ligand NETA. Bioorg. Med. Chem. Lett. 2008, 18, 3436-3439.

    Chong HS, Ma X, Le T, Kwamena B, Milenic DE, Song HA, Brady ED, Brechbiel MW. Rational Design and Generation of Bimodal Bifunctional Ligand for Antibody-Targeted Radiation Cancer Therapy. J. Med. Chem. 2008, 51, 118–125.

    Chong HS, Ma X, Lee HS, Bui P, Song HA, Birch N. Synthesis and evaluation of novel polyaminocarboxylate-based antitumor agents. J. Med. Chem. 2008, 51, 2208–2215.

    Chong HS, Song HA, Lim SY, Macrenaris K, Ma X, Lee HS, Bui P, Meade T. Novel cholic acid-based contrast enhancement agent for targeted MRI. Bioorg. Med. Chem. Lett. 2008, 18, 2505–2508.

    Birch N, Wang X, Chong HS. Iron Chelators as Therapeutic Agents. Expert Opinion in Therapeutic Patents (Invited Review). 2006, 16, 1533–1556.

    Professional Society Memberships

    Editorial Board Service

    Professional Society Service

    Grants

    Community Service

    Ishaque Khan
    Department of Biological, Chemical and Physical Sciences

    In science, what's small is big.'The heart and soul of today's scientific revolution is nanoscale science,' says Professor Ishaque Khan. more...

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