Sameer Varma, Ph.D.

Assistant Research Professor

Office: Room 134 University Technology Park
Office Hours:
Phone: 312.567.3741
Fax: 312.567.3494
Email: svarma@iit.edu
Web:

Expertise

• Computational chemistry
• Quantum and molecular mechanics simulations
• Membrane proteins
• Ligand-substrate interactions

Education

• B.S. Indian Institute of Technology
• Ph.D. University of Illinois

Curriculum Vitae

Research & Major Accomplishments

Current Projects

Awards/Honors

Patents

Books

Selected Publications

D. Asthagiri, P.D. Dixit, S. Merchant, M.E. Paulaitis, L.R. Pratt, S.B. Rempe & S. Varma, Ion selectivity from local configuration of ligands in solutions and ion channels. Chem. Phys. Letts. 485: 1-7, 2010. Cover Article

S. Varma & S.B. Rempe, Structural transitions in ion coordination driven by changes in competition for ligand binding. J Amer. Chem. Soc. 130, 15405-15419, 2008.

S. Varma, D. Sabo & S.B. Rempe, K+/Na+ selectivity in K-channels and Valinomycin: Over-coordination Vs Cavity-size constraints. J Mol. Biol. 376, 13-22, 2008.

S. Varma & S.B. Rempe, Tuning ion coordination architectures to enable selective partitioning. Biophys J. 93, 1093-1099, 2007. New & Notable article

S. Varma & E. Jakobsson, The cPLA2 C2α Domain in Solution: Structure and Dynamics of its Ca2+-activated and Cation-free States. Biophys. J., 92, 966-976, 2007.

S. Varma, S. W. Chiu & E. Jakobsson, The influence of amino acid protonation states on molecular dynamics simulations of a bacterial porin OmpF. Biophys. J., 90, 112-123, 2006.

N.J. Malmberg, S. Varma, E. Jakobsson and J.J. Falke, Ca2+ Activation of the cPLA2 C2 Domain: Ordered Binding of Two Ca2+ Ions with Positive Cooperativity. Biochemistry, 43, 16320-16328, 2004.

Professional Society Memberships

Editorial Board Service

Professional Society Service

• American Chemical Society
• Biophysical Society

Grants

Community Service