Renal Disease and Injury
(Cassel, Hammes (UC), Williamson)
Research is conducted in collaboration with Hines VA Hospital (Dr. Karen A. Griffin) on the effects of blood pressure (BP), BP power spectra on pressure-flow relationships, and transfer functions in the kidneys. The effects of obesity, dynamic BP transmission and susceptibility to glomerular injury, and the dynamics of BP transmission and hypertensive renal injury are also studied by Professor Williamson and his colleagues at Hines VA Hospital.
Professor Cassel is collaborating with University of Chicago researchers (Dr. Mary Hammes) on developing a computational model of cephalic arch hemodynamics in end-stage renal disease patients with arterial venous fistulas. The model enables simulation studiess to determine some of the relevant physical phenomena that occur for various Reynolds number (flow speed) regimes and geometries.