 our experience | our people | our facilities | our services 
Boasting over 35 years of experience, our Inhalation Toxicology Division is a trusted provider of research for the chemical, pharmaceutical, and biotechnology industries. During these years, we have conducted numerous subchronic and chronic studies on a wide range of chemicals and pharmaceuticals for both commercial sponsors and the National Toxicology Program (NTP). We specialize in performing reproductive and neurotoxicological studies using the inhalation route of exposure. Our staff conducts testing of sensory irritants and pulmonary sensitizers used in occupational exposure assessments. Another area of expertise within the Inhalation Toxicology Division is the capability to monitor pulmonary parameters such as tidal volume, respiration rate, and compliance. These parameters are particularly important to establish the dosimetry of inhaled drugs and chemicals and to understand their effects on the respiratory system. All studies are conducted in accordance with Good Laboratory Practice (GLP) Regulations satisfying all current TSCA, OECD, EEC, FIFRA, and FDA guidelines for regulatory submission.   
The Inhalation Toxicology staff is the hallmark of our capability and expertise. This division is managed by an aerosol physicist (Ph.D.) who is well experienced in developing methods for generating atmospheres with chemicals or drugs having extremely difficult properties that complicate the vaporization or aerosolization process. Our inhalation engineers (B.S.), analytical chemists (Ph.D.), and toxicologists (Ph.D. and D.A.B.T.) are proficient with atmospheres ranging from simple gases or aerosols to complex mixtures like smoke atmospheres. Collectively, their expertise is demonstrated in the generation and characterization of the atmospheres, in the correlation of the atmosphere concentrations with the biological effects and, ultimately in the interpretation of the study results. 
Our inhalation exposure laboratories are well equipped with a wide array of nose-only (including the single pass, non-rebreathing system) and whole-body inhalation chambers, test atmosphere generation, and monitoring systems. The inhalation toxicology facility is approximately 13,000 square feet and is comprised of seven inhalation exposure and animal holding laboratories, incorporating a clean/dirty corridor system. 
Exposure Atmosphere:
To learn more, please contact Dr. Narayanan Rajendran |
