Professional Interests
My research focuses on the chemistry and biochemistry of the oxidant,
singlet molecular oxygen, 1O2. Using generation methods developed
at atmospheric pressure I am studying the gas-phase reactions of 1O2
with polycyclic aromatic hydrocarbons as a possible source of
environmental carcinogens. I am also interested in the biological
effects of singlet oxygen. Having demonstrated the cytotoxity and
genotoxity of 1O2 I am seeking to identify the sites and mechanisms of
the 1O2 cytotoxity.
The mechanisms of polycyclic aromatic hydrocarbon (PAH)
transformations are also of interest. The photo-oxidation of PAH on
model particulate is being studied to determine the oxidants including
1O2 responsible for these transformations.
Representative Publications
- Oxidation of Phosphatidylcholine Membranes by Singlet Oxygen
Generated in the Gas Phase, W. C. Eisenberg, J. Anand, S. Wang
and R. J. Stevenson, Photochemistry and Photobiology 56,
441-445 (1992)
- Atmospheric Gas Phase Generation of Singlet Delta Oxygen, W. C.
Eisenberg, Advances in Oxygenated Processes, Vol. 3, pp 71-113,
JAI Press, Inc., London, 1991.
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