Andrew J. Howard Associate Professor of Biology Associate Professor of Physics Co-Director, Masters in Health Physics Program
	B.S.:	Pomona College
	Ph.D.:	University of California, San Diego
	Office:	174B Life Sciences Building
	Phone:	312.567.5881       Fax:  312.567.3576
	e-mail:	howard@iit.edu
	Howard's Web page

Professional Interests

Macromolecular Crystallography, including methods development; application of synchrotron radiation to biological structure research; crystallographic computer software development; structure determination of chirally selective antibodies; structural studies of cytochrome C peroxidase; structures of proteins found during gene-sequencing efforts.

Introduction to the Professions; a freshman survey course dealing with the realities of science and a scientific career. The course includes discussions of the definition of science, the tools of science, science as a career, safety in science, the history and philosophy of science, and similar subjects. Assignments include numerous exercises in writing, because writing is essential to the effective conduct of science. The course features an opportunity for students to present results orally, and it includes at least one field trip during the semester. Textbook: James Trefil, 101 Things You Don't Know About Science and No One Else Does Either (New York: Houghton Mifflin, 1997), 355pp., paper.

Health Physics: As co-director of IIT's Masters in Health Physics program, I endeavor to bring students of this discipline together with experts in the field. I'm not a health physicist myself, but I do teach radiation biophysics as a component of this program, and I am developing some understanding of the rest of the field.

Representative Publications

• Alexey Teplyakov, Kap Lim, Peng-Peng Zhu, Geeta Kapadia, Celia C. H. Chen, Jennifer Schwartz, Andrew Howard, Prasad T. Reddy, Alan Peterkofsky, and Osnat Herzberg (2006) "Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein", Proc. Natl. Acad. Sci.103: 16218-16223.
  
  
• Park, K.-W., Webster, D.A., Stark, B.C., Howard, A.J., and Kim, K.-J. (2003) Fusion protein system designed to provide color to aid in the expression and purification of proteins in Escherichia coli. Plasmid 50: 169-175.
  
  
• Eisenstein, E., Gilliland, G.L., Herzberg, O., Moult, J., Orban, J., Poljak, R.J., Banerjei, L., Richardson, D., and Howard, A.J. (2000) Biological function made crystal clear - annotation of hypothetical proteins via structural genomics. Current Opinions in Biotechnology 11: 25-30.
  
  
• Howard, A. (1999) Macromolecular crystallography at third-generation synchrotron sources. Chapter for Third-Generation Hard X-Ray Synchrotron Radiation Sources: Source Properties, Optics, and Experimental Techniques, D. Mills, ed. Wiley: 1999, ISBN 0471314331.
  
  
• Howard, A. (1998) Participation of pharmaceutical companies in synchrotron radiation research. Nature Structural Biology 5: 623-626.
  
  

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