Rong Wang Associate Professor of Chemistry Associate Chair for Chemistry
	B.S.:	Jilin University
	Ph.D.:	University of Tokyo
	Office:	164 Life Sciences
	Phone:	312.567.3121       Fax:  312.567.3494
	e-mail:	Rong.Wang@iit.edu
	Wang's Web page

Professional Interests

My research interest focuses on the development and application of novel materials, tools and methods to enable researches in bioscience that can’t be achieved using conventional biological tools and/or methods. In specific, the research in my group harnesses the advancements in molecular characterization methods such as probe scanning microscopy, surface engineering with new bio-conjugate chemistry, and molecular manipulation via photochemistry and nano-processing to examine the biological systems in vivo on the nanometer scale, which will lead to the clarification of the mechanism of a biological event at molecular level. In addition, I am interested in fabricating nanoscale devices for biosensing at single protein level.

Around these central themes, three interlaced research efforts have been made. First, we developed methods for in situ mapping, visualization and real time function characterization of individual proteins on a living cell membrane. The outcome of the research allows the study of ligand-receptor interaction in living cells in a dynamic manner, bridging the real-time function of individual protein to the cell activity. Secondly, we developed methods for in situ structure characterization at nano-meter resolution. For example, we were able to examine and reveal the characteristic surface features of bacterial spore coats under natural environments. The research provides phenotypic approach for finger-printing spore species and strains, useful for fundamental studies and forensic investigation. The third effort of my group is to perform nano-manipulation of materials. The research is to generate nano-devices for ultra-high sensitivity detection.

Representative Publications

• “Protein Delivery with Nanoscale Precision”, Qiling Tang, Yuexing Zhang, Liaohai Chen, Funing Yan and Rong Wang, Nanotechnology, 16, 1062-1068 (2005).
  
  
• "Synthesis and characterization of a novel photolabile cross-linker and its application on protein photo-delivery", F. Yan; L. Chen; Q. Tang; R. Wang, Bioconj. Chem., 15, 1030-1036 (2004)
  
  
• "Identification of TrkA on living PC12 cells by the atomic force microscopy" Chada, V.G.R.; Malinowska, K.; Menhart, N.; Wang, R., Biochim. Biophys. Acta.,1667, 15-25 (2004).
  
  
• "Studies on Protein-Receptor Interaction Using the Atomic Force Microscope", S. Vengasandra, G. Sethumadhavan, F. Yan and R. Wang, Langmuir, 19, 10940 (2003).
  
  
• "Morphogenesis of Bacillus Spore Surfaces" V.G.R. Chada, R. Wang, E.A. Sanstad and A. Driks, J. Bacteriol., 185, 6255 (2003).
  
  

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