Professional Interests
Dr. Ke Zhang is trained in physics and biophysics with extensive experience in x-ray experiments on metalloproteins and other systems. He has worked continuously on x-ray absorption spectroscopy. These include numerous XAFS studies of metalloproteins, especially zinc proteases. More recently, he has worked on XAFS instrumentation oriented projects, such as the development of a stop-flow system, the dead time correction of the Ge detector, and polarized XAFS on a single monolayer of protein. Since 1997 he has worked primarily on x-ray detector development. He founded HD Technologies, Inc. in 1997. The primary business of the company is the research and development of various multilayer analyzer array detectors for x-ray fluorescence detection at synchrotron sources.
Representative Publications
- K. Zhang, R. Liu, and D. Auld, A Versatile Rapid Mixing and Flow Device for X-ray Absorption Spectroscopy, J. Synchrotron Rad. 11, 204-208, 2004.
- K. Zhang, G. Rosenbaum, and G. Bunker, Energy-resolving x-ray fluorescence detection using synthetic multilayers, Journal of Synchrotron Radiation, 5, 1227-1234 (1998).
- K. Zhang, and D. S. Auld, XAFS Studies of Binary and Ternary Complexes of Carboxypeptidase A, Biochemistry, Vol. 35, 16306 (1995).
- K. Zhang and D.S. Auld, XAFS Studies of Carboxypeptidase A: Detection of a Structural Alteration in the Zinc Coordination Sphere Coupled to the Catalytically Important Alkaline pKa, Biochemistry 32, 13844, (1993) .
- K. Zhang, E. A. Stern, J. J. Rehr, and F. Ellis, Double Electron Excitation in X-ray Absorption of Xenon Atoms, Phys. Rev. B, 44, 2031 (1991).
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