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The mission of the Magnetic Resonance Imaging Lab at the Illinois Institute of Technology (MRIIT for short; pronounced 'emrit ) is to develop MRI data acquisition, image reconstruction and processing techniques, and to apply these methods for the diagnosis and monitoring of brain disease. MRIIT is part of the Medical Imaging Research Center and the Pritzker Institute of Biomedical Science and Engineering.

MRIIT is home of the IIT Human Brain Atlas. The atlas contains: anatomical, DTI, HARDI templates, probabilistic gray matter labels, and probabilistic connectivity-based multi-layer white matter labels. To download the atlas, please click on the Downloads button.

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New Paper [Jun 2018]

Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics.

Brain Imaging Behav 2018 (in press)

New Paper [Jun 2018]

Neopterin is associated with hippocampal subfield volumes and cognition in HIV.

Neurol Neuroimmunol Neuroinflamm 2018;5:e467

New Paper [May 2018]

Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults.

Neurobiol Aging 2018;69:177-184

New Paper [Feb 2018]

Accelerometer Physical Activity is Associated with Greater Gray Matter Volumes in Older Adults without Dementia or Mild Cognitive Impairment.

J Gerontol B Psychol Sci Soc Sci 2018 (in press)

New Paper [Jan 2018]

Evaluation of standardized and study-specific diffusion tensor imaging templates of the adult human brain: Template characteristics, spatial normalization accuracy, and detection of small inter-group FA differences.

Neuroimage 2018;172:40-50

MarkVCID meeting [Jan 2018]

Dr. Arfanakis presented at the MarkVCID second annual meeting of participating sites.

MarkVCID 2018, Los Angeles, California

New Paper [Dec 2017]

Ex-vivo quantitative susceptibility mapping of human brain hemispheres.

PLoS One 2017;12:e0188395.

New Paper [Dec 2017]

Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.

JAMA Neurol 2017;74:1473-1480.


    Current research at MRIIT focuses on: a) human brain atlases, and b) multi-modal in-vivo and ex-vivo MRI in aging and dementia. Just a few examples of our projects are:

  • Development of brain atlas resources for neuroimaging research
  • Development of translational ex-vivo brain MRI techniques
  • Development of MRI-based biomarkers of age-related neuropathology
  • Multi-modal in-vivo MRI investigation of aging

  • Publications