Thomas C. Irving

  • Professor of Biology and Physics
  • Executive Associate Chair, Biology Division, BCS Department
  • Director, Biophysics Collaborative Access Team (BioCAT)
  • Professor of Biomedical Engineering

Education

Ph.D. University of Guelph
M.Sc. University of Guelph
B.Sc. University of Guelph

Research Interests

Operate a NIH funded Biotechnology Research Center at the Advanced Photon Source, Argonne National Laboratory for non-crystalline diffraction and scattering from biological molecules and tissues.

  • perate a Biotechnology Research Center at the Advanced Photon Source for non-crystalline diffraction scattering and x-ray spectroscopy of biological molecules, collaboration with NIH/NCRR
  • Deduce the structural and functional l roles of My-BP-C in cardiac muscle contraction, collaboration with University of Wisconsin/NIH
  • Deduce the structural and functional and structural roles of titin in muscle contraction, collaboration with University of Arizona/NIH

Professional Affiliations & Memberships

  • American Crystallographic Association
  • American Physical Society Division of Biological Physics
  • Biophysical Society
  • Sigma Xi

Awards

  • Ontario Scholar (1974)
  • I.O.D.E. Capt. Frederick Bond Memorial University Entrance Scholarship
  • Ontario Graduate Scholarship (1983-84)(1985-86)
  • Canadian Heart Foundation Post-doctoral Fellowship (1989 - 1991)
  • IITRI fellow (1998- 2000)
  • Sigma Xi / IIT Award for Excellence in University Research (senior division) 2007

Publications

Projects

  • Determine the Structural Basis of the Frank-Starling Law of the Heart, collaboration with Loyolla University Stritch School of Medicine.
  • Deduce the structural and functional l roles of My-BP-C in muscle contraction, collaboration with University of Massachusetts Medical School.
  • Study the deleterious effect of mutations in the myosin light chains in cardiomyopathies, collaboration with University of Miami Medical School.
  • Deduce the structural and functional and structural roles of nebulin in muscle contraction and their role in nemaline myopathy, collaboration with University of Arizona/NIH.
  • Deduce the structural mechanism of delayed stretch activation in striated muscle, collaboration with Duke University Medical School.

Editorial Boards

  • Frontiers in Molecular Biosciences, review editor

Expertise

  • Biophysics of muscle contraction, non-crystalline x-ray diffraction, synchrotron radiation instrumentation
Thomas Irving

Contact Information

312.567.3489 312.567.3494 166A Robert A. Pritzker Science Center