Thomas C. Irving

  • Professor of Biology and Physics
  • Director, Biophysics Collaborative Access Team (BioCAT)
  • Professor of Biomedical Engineering


Ph.D. University of Guelph
M.Sc. University of Guelph
B.Sc. University of Guelph

Research Interests

Muscle structure, function and regulation

Professional Affiliations & Memberships

  • American Crystallographic Association
  • American Physical Society Division of Biological Physics
  • Biophysical Society
  • Sigma Xi
  • American Heart Association
  • AAAS


  • Ontario Scholar (1974)
  • I.O.D.E. Capt. Frederick Bond Memorial University Entrance Scholarship
  • Ontario Graduate Scholarship (1983-84)(1985-86)
  • Canadian Heart Foundation Post-doctoral Fellowship (1989 - 1991)
  • IITRI fellow (1998- 2000)
  • Sigma Xi / IIT Award for Excellence in University Research (senior division) 2007


A complete list can be found at 


  • Determine the Structural Basis of the Frank-Starling Law of the Heart, collaboration with Loyola University Stritch School of Medicine.
  • Deduce the structural and functional l roles of My-BP-C in muscle contraction, collaboration with University of Massachusetts Medical School.
  • Study the deleterious effect of mutations in the myosin light chains in cardiomyopathies, collaboration with University of Miami Medical School.
  • Deduce the structural and functional and structural roles of nebulin in muscle contraction and their role in nemaline myopathy, collaboration with University of Arizona/NIH.
  • Deduce the structural mechanism of delayed stretch activation in striated muscle, collaboration with Duke University Medical School.

Editorial Boards

International Journal of Molecular Science


Discipline: Biophysics

     Subfields: Muscle, motility, macromolecular small-angle X-ray diffraction and scattering


Discipline: Synchrotron radiation research

     Subfields: Applications of synchrotron small angle diffraction to biophysical problems


Thomas Irving

Contact Information

312.567.3489 312.567.3494 166A Robert A. Pritzker Science Center